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Motexafin lutetium : ウィキペディア英語版
Motexafin lutetium

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Motexafin lutetium is a texaphyrin, marketed as Antrin by Pharmacyclics Inc.
It is a photosensitiser for use in photodynamic therapy to treat skin conditions and superficial cancers.
It has also been tested for use in photoangioplasty (photodynamic treatment of diseased arteries).〔(Pharmacyclics Announces Final Phase 1 Results of Antrin Phototherapy For Coronary Artery Disease ), 2002〕
It is photoactivated by 732 nm light which allows greater depth of penetration.〔http://findarticles.com/p/articles/mi_qa3931/is_200909/ai_n42040200/pg_9/ Porphyrin and Nonporphyrin Photosensitizers in Oncology: Preclinical and Clinical Advances in Photodynamic Therapy Photochemistry and Photobiology, Sep/Oct 2009. by O'Connor, Aisling E, Gallagher, William M, Byrne, Annette T〕
==Clinical trials==
Phase II clinical trials were in progress in 1999.〔(Antrin Photoangioplasty Phase II Clinical Trial Patient Treated During Live Case Demonstration at TCT ), 1999〕
A phase I trial for prostate cancer reported in 2009.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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